Volume( 1) - Issue( 1) 2019 pp 5 DOI: 0

Immune Helminthic Therapy of Inflammatory Bowel Disease using Tricuris Suis Ova.

Title

Immune Helminthic Therapy of Inflammatory Bowel Disease using Tricuris Suis Ova.

Abstract

Background: Inflammatory bowel diseases (IBD) include ulcerative colitis and Crohn’s disease. It is a disease with idiopathic aetiology with Th1 predominant immune reaction.  The study of immune modulation mechanisms by parasites is becoming a multidisciplinary topic with a number of cross-links to other areas of research. Knowledge of the intricacies of immune modulation, combined with prolonged research into the underlying mechanisms of autoimmune diseases, has directed present-day studies towards focusing on what is generally termed "Helminthic Therapy" and recently described as one type of immune therapy.Objectives: To raise a research question whether induced helminthic infections in certain intensity as immune therapy can be effective in treating autoimmune IBD.

Keywords

TSO treatment, immune modulation, Crohn's disease